Pdf preparation, optimization and swelling study of. Synthesis of carboxymethyl starch grafted poly methacrylic acids. In pharmaceutical industry cms ssg is used as a swelling agent. Synthesis and ph sensitivity of carboxymethyl chitosan.
Carboxymethyl sago pulpcarboxymethyl sago starch hydrogel. Synthesis conditions such as reaction temperature, concentration of sodium hydroxide, amount of etherifying agent such as sodium monochloroacetate and reaction time of carboxymethylation were used to achieve the highest degree. Water absorbency was reduced with increasing the amounts of polymer and crosslinker, in contrast with gel content results. Preparation and characterization of irradiated carboxymethyl sago starch acid hydrogel and its application as metal scavenger in aqueous solution abstract carboxymethyl sago starch acid hydrogel was prepared via irradiation technique to remove divalent metal ions pb, cu and cd from their aqueous solution. Their swelling improved with added carboxymethyl group on the starchepichlorohydrin structure. Effect of carboxymethylation on physicochemical and release characteristics of indian palo starch. An in situ hydrogel based on oxidation cholesterol starch ocs and o carboxymethyl chitosan cmct that is completely devoid of potentially cytotoxic small molecule crosslinkers and does not require complex manoeuvres or catalysis has been formulated and characterized. The preparation method of the present invention is simple, can form fullbodied aqueous solution or hydrogel, and the preparation of hydrogel is without adding other organic solvent any or chemical crosslinking agent under. Synthesis, characterization and application tadeusz spychaj, katarzyna wilpiszewska and magdalena zdanowicz polymer institute, west pomeranian university of technology, szczecin, poland carboxymethyl starch cms could.
Carboxy methyl starch cms carboxy methyl starch cms is a watersoluble polysaccharide which is widely employed as an additive. Carboxymethyl cellulose sodium salt acros organics with an average molecular weight of 90000 and ds 0. Xrd analysis confirmed the formation of cu nanoparticles in the. Proposed crosslinking model for carboxymethyl cellulose. Synthesis of carboxymethyl starchbiobased epoxy resin and their impact on mechanical properties. Synthesis of carboxymethylcellulosestarch superabsorbent. Application of carboxymethyl polysaccharides as biosorbents. Viscoelastic and rheological properties of carboxymethyl. Sodium carboxymethyl cellulose nacmc and carrageenan cg hydrogels were synthesized for potential use in the growth of wheatgrass plant. Preparation and characterization of irradiated carboxymethyl sago starchacid hydrogel and its application as metal scavenger in aqueous solution abstract carboxymethyl sago starchacid hydrogel was prepared via irradiation technique to remove divalent metal ions pb, cu and cd from their aqueous solution. The hydrogel is expected to be a drug delivery system carrier for protein drugs. Sodium carboxy methyl starch referred to as cms is a starch ether derivative derived from starch.
An inventive hydrogel comprises an inventively crosslinked carboxymethyl starch and water. It has attracted much attention due to its ability to prolong ophthalmic drug retention 12. Carboxymethylcellulose, carboxymethyl starch, and alginic. Characterization and properties of carboxymethyl cellulose. Crosslinked, longtime stable carboxymethyl starch as an. Electrically conductive cellulosebased hydrogels are prepared by a. Polyelectrolyte complexation versus ionotropic gelation. Potency of poly acryliccarboxymethyl starchchitosan. Recently, a novel biopolymeric nanocomposite hydrogel comprised of in situ formed silver nanowires agnws deposited chemically crosslinked carboxymethyl cellulose cmc has been developed, which demonstrates superior efficacy as anticancer drugcurcumin carrier. The effect of the solution concentration on the crosslinking of cms, the properties of formed hydrogel and the biodegradability were investigated.
The grooved surface of carboxymethyl sago starch acid hydrogel caused an increase in its surface area. In situ crosslinkable hydrogels formed from modified starch. Cms is an important modified starch with unique properties due to the presence of negatively charged functional group ch2coo. Such a hydrogel can furthermore contain a one or more preservatives andor b glycerine.
Hydrogels based on carboxymethyl cassava starch cross. Effect of polymer mixing ratio and study of controlled drug release. Removal of dyes and heavy metal ions from water by. The synthesis of carboxymethyl cellulosebased hydrogel from sugarcane bagasse using microwaveassisted irradiation for selective. Superabsorbent hydrogel was prepared by epichlorohydrin crosslink of cassava starch. Preparing a novel superabsorbent based on carboxymethyl biocomposite. Citric acid was used as cross linker to avoid the cytotoxicity of conventional cross linkers. Properties of the crosslinked cmccms blend hydrogels such as gel fraction, degree of swelling sw, gel.
Highenergy irradiation allows the chemical crosslinking without the use of crosslinking agents, while the introduction of other natural or. Hydrogels prepared at a ratio of 11 had a swelling percentof432546%whencmcwasaddedontocs,while. The morphological observation of hydrogels reveals the porous structure for the. Volume 45, issue 12, december 2009, pages 33993408. Herein, we report for the first time that carboxymethyl chitosan cmch can exhibit strong blue fluorescence at. Removal of heavy metal ions by polyvinyl alcohol and. Examples of such hydrogel is a hydrogenbound cmc carboxymethyl cellulose network formed by dispersing cmc into 0. The swelling capacity of hydrogel was found to be dependent upon ph. Thus, the adsorption capacities of the carboxymethyl sago starchacid hydrogel for lead, copper and cadmium were relatively high and were found to be 109. In this study, sago starch was modified in order to enhance its physicochemical properties. The morphological observation of hydrogels reveals the porous structure for the copolymerized gels.
A method of manufacturing the polyelectrolyte complex is also provided. The resultant cmchzn sample exhibits a typical fluorescence lifetime of. Sodium carboxy methyl starch cms sunray international. Application of carboxymethyl polysaccharides as bio. Properties of the crosslinked cmccms blend hydrogels such as gel fraction, degree of swelling sw, gel strength, and biodegradability were investigated. Preparation and characterization of carboxymethyl sago waste. The structure and properties of starchepichlorohydrincarboxymethyl hydrogel were measured by sem, ftir, water and physiological solution absorption test and water retention test. Uncrosslinked carboxymethyl cellulose cmc starch blend used to prepare two hydrogels.
Preparation of carboxymethyl sago pulp hydrogel from sago waste by electron beam irradiation and swelling behavior in water and. Radiation crosslinking of carboxymethyl starch sciencedirect. The degree of substitution of the cmss obtained was. Superabsorbent hydrogels based on natural polymer, carboxymethyl cellulose cmcsodium alginate sa were prepared by 60co. The bulk of cms rise thirty times after swelling, which can accelerate swelling of tablet and the dissolution of effective component. Hydrogel network formation due to intermolecular hbonding in cmc at low ph. In situ crosslinkable hydrogels formed from modified. Carboxymethyl chitosan is an important watersoluble polysaccharide with low toxicity, good biocompatibility and biodegradability 11. Carboxymethylation was used to introduce a carboxymethyl group into a starch compound. Carboxymethyl sago waste cmsw was prepared under heterogeneous condition as the product of the sago waste and sodium monochloroacetate smca in presence of sodium hydroxide naoh. The focuses of this study were to investigate the effect of sodium montmorillonite clay mmtna content on the physical properties and extent of enzymatic hydrolysis polyvinyl alcohol pva. The hydrogel showed typical amphoteric character responding to ph of the external medium. Hydrogels based on carboxymethyl cassava starch crosslinked with di or polyfunctional carboxylic acids.
Okieimen2 1polymer technology department, auchi polytechnic, auchi, nigeria 2biomaterials research centre, department of chemistry, university of benin, benin city, nigeria. A crosslinked carboxymethyl starch is described for use as an absorbent for water. Synthesis and characterization of chitosancarboxymethyl. Auda jabbar braihi, sihama issa salih, fadhel abbas hashem, viscoelastic and rheological properties of carboxymethyl cellulose starchgraphite oxide as superabsorbent hydrogel nano composites shncs, international journal of materials science and applications. Hbonded hydrogel can be obtained by lowering the ph of aqueous solution of polymers carrying carboxyl groups. The hydrogels are physically characterized by the swelling ratio and gel fraction. A crosslinked carboxymethyl starch is described for use as an absorbent for water, whereby the crosslinking in part or in full takes place via diether bridges, which are formed between neighbouring polymer chains. Crosslinked xanthan gumstarch hydrogels as promising. A new biodegradable starch derivative hydrogel, carboxymethyl starch cms hydrogel, was synthesized by irradiation in high concentrated solution in the socalled pastelike condition. Effect of nanofillers on carboxymethyl cellulosehydroxyethyl cellulose hydrogels. Novel polyampholyte hydrogels based on carboxymethyl chitosans cmc of various degree of deacetylation dd and substitution ds were prepared by crosslinking with glutaraldehyde. Differences in morphology, ph, and electric charge of chitosan cs based hydrogels prepared by complexation with carboxymethylcellulose cmc, carboxymethylated starch cms, and alginic acid aa at different polymers ratios and changing the order of addition were studied. The invention provides a kind of low concentration low degree of substitution carboxymethyl curdlan aqueous solution or hydrogel and its preparation method and application. In animal studies with real wounds, moderate to heavy blood flow was stopped in less than one minute.
These metrics are regularly updated to reflect usage leading up to the last few days. The swelling capacity of hydrogel was quite higher than most of. Characterization of superabsorbent hydrogel based on. That is how the ability to control the properties and functionalities of hydrogel broadens the understanding of possible cellmatrix. Preparation and characterization of nanoporous sodium. Hydrogel nanofibers from carboxymethyl sago pulp and its. Enhanced fluorescence of carboxymethyl chitosan via metal. Preparation of poly acrylicstarch hydrogel and its application for cadmium ion removal from aqueous solutions. View enhanced pdf access article on wiley online library html view download pdf for. Some properties of chemical crosslinking biohydrogel from. Sodium carboxy methyl starch cms or scms is a starch ether derivative derived from starch. The results of this work have revealed that films with mmtna content at 5 wt% exhibited a significantly reduced.
Nov 15, 2019 to develop a new drug delivery approach, carboxymethyl cellulosecu bionanocomposite hydrogels were successfully prepared in situ during the formation of cu nanoparticles within swollen carboxymethyl cellulose hydrogels. Jan 02, 2014 a carboxymethyl starch and chitosan polyelectrolyte complex is provided. Effect of experimental parameters on the formation of. The effect of different ratios of sa 20, 30, 40, and 50% on the physical properties of the cmcsa hydrogel such as gel fraction percentage gf%, and swelling percentage sw% were investigated. It is soluble in water at room temperature and forms a transparent to light milky and viscous solution. Synthesis and in vitro characterizations of porous. Radiation synthesis of superabsorbent hydrogels based on. Synthesis and characterization for biomedical applications elrefaie kenawy a, elbadawy a.
Cn106188574a a kind of carboxymethyl curdlan aqueous. The objective of this work was to study differences in morphology and surface charge of hydrogels prepared by ionotropic gelation, polyelectrolyte complexation, and a combination of both methods. May 30, 2017 superabsorbent hydrogels show a large potential in a wide array of applications due to their unique properties. In this study, carboxymethyl starch cms was synthesized by reacting native sago starch with sodium monochloroacetate through singlestep etherification reaction. An in situ hydrogel based on oxidation cholesterol starch ocs and ocarboxymethyl chitosan cmct that is completely devoid of potentially cytotoxic small molecule crosslinkers and does not require complex manoeuvres or catalysis has been formulated and characterized. A novel superabsorbent was prepared by utilizing carboxymethyl starch and carboxymethyl cellulose biocomposites as a grafting backbone. Cellulosebased hydrogels for agricultures request pdf. Viscoelastic and rheological properties of these two hydrogels were studied and compared. Novel magnetic nanocomposite hydrogel mcvp beads were prepared by instantaneous gelation of carboxymethyl starchgpolyvinyl. Superabsorbent polymer sap blend has been synthesized from carboxymethyl cellulose cmc, starch, and aluminum sulfate octadecahydrate crosslinker. Synthesis and characterization of chitosan carboxymethyl starch hydrogels as nano carriers for colonspecific drug delivery article pdf available january 2010 with 216 reads how we measure. Synthesis, water absorbent behavior and rheological characterizations. The water absorbency and gel content properties of prepared hydrogels were investigated.
An optimization study via response surface methodology. Superabsorbent hydrogels based on natural polymer, carboxymethyl cellulose cmcsodium alginate sa were prepared by 60 co. Pazdzioch, carboxymethyl starchmontmorillonite composite microparticles. Superabsorbent hydrogels show a large potential in a wide array of applications due to their unique properties. The maximum swelling capacity of hydrogel was recorded as 32. Researcharticle preparation and characterization of nanoporous sodium carboxymethyl cellulose hydrogel beads gulenoytunakalin 1 andmehlikapulat2 scientic.
The degree of substitution of the cmss obtained was 0. Thus, the adsorption capacities of the carboxymethyl sago starch acid hydrogel for lead, copper and cadmium were relatively high and were found to be 109. Optimization of synthesis condition for carboxymethyl cellulosebased hydrogel from rice straw by microwaveassisted method and its application in heavy metal ions removal. The adsorption efficiency of starch based hydrogel nanocomposite was found to be 7. In situ hydrogel constructed by starch based nanoparticle and polyvinylamine via a schiff base reaction is used to test the controlled release of doxorubicin. Networks of carboxymethyl starch and acrylonitrile. Preparation, optimization and swelling study of carboxymethyl. Download hires image download to mspowerpoint cite this. Prepared hydrogels exhibit protein adsorption and release abilities. Pdf synthesis of carboxymethyl starchbiobased epoxy. The crosslinked polymer has been prepared by grafting poly 2methacryloyloxy ethyl trimethylammonium chloride on cmc using.
Effect of native cassava starchpoly sodium acrylateco acrylamide hydrogel on the growth performance of maize zea may seedlings l. Water absorption capacity wac, ftir, sem, dsc, cho, flame photometer and ignition tests are carried out to determine the used cmc formula, investigate the crosslinking process, and suggest a crosslinking model. Jul 10, 2017 superabsorbent hydrogel was prepared by epichlorohydrin crosslink of cassava starch. Carboxymethyl cellulose cmc nanocomposites using enzyme.
Removal of dyes and heavy metal ions from water by magnetic. Full length research paper a comparative study of cmc. Carboxymethyl sag o pulp cmsp carboxymethyl sago starch cmss hydrogel was synthesized by electron beam irradiation. Preparing a novel superabsorbent based on carboxymethyl. Synthesis of sodium carboxymethyl starch from high amylose starch for the application of controlled release matrix for oral medications has been reported in. Carboxymethyl starch sodium carboxy methyl starch for. A carrier comprising this polyelectrolyte complex along with a solid oral dosage form comprising this polyelectrolyte complex are also provided. Method of carboxymethyl starch by titration iso 112161998 geneva. Where, ws is the weight of hydrogel in swollen state and wd is the weight of hydrogel in dry state 8. Mar 04, 2019 the current work reports the synthesis of carboxymethyl cellulose cmc and xylanbased homopolymerized as well as copolymerized hydrogels using an ethylene glycol diglycidyl ether crosslinker in alkaline medium. Biodegradable blend hydrogels based on carboxymethyl cellulose cmc and carboxymethyl starch cms were prepared by the radiationinduced crosslinking. Facile preparation of carboxymethyl cellulosecu bio. International journal of biological macromolecules, 77, 181187. The work was intended to develop a novel acrylic acid grafted hydrogel by chemical crosslinking of xanthan gum and starch under microwave irradiation.
The preparation of gels by charge interaction methods has been extensively studied, but it is not yet clear how these methods influence gel characteristics. The carboxymethyl sago starch cmss was used to prepare smart hydrogel by adding acetic acid into the cmss powder as the crosslinking agent. Cmccs and aacs hydrogels were amorphous and porous threedimensional networks, with smaller pores at higher anionic. Controlled release behavior of zincloaded carboxymethyl. To develop a new drug delivery approach, carboxymethyl cellulosecu bionanocomposite hydrogels were successfully prepared in situ during the formation of cu nanoparticles within swollen carboxymethyl cellulose hydrogels. Synthesis of carboxymethyl starch biobased epoxy resin and their impact on mechanical properties. May 01, 2004 read synthesis and characterization of cross. This study also demonstrated that the fabrication of cms materials can be achieved in the facile and environmentally friendly system. Cellulose and its derivatives such as carboxymethyl cellulose cmc have been employed as a biomaterial for their diverse applications such as tissue engineering, drug delivery and other medical materials. Effect of native cassava starchpoly sodium acrylateco. Effect of nanofillers on carboxymethyl cellulosehydroxyethyl. The difference in concentration of mobile ions in the hydrogel interior relative to external solution osmotic pressure, changes in solvent ph, drives the volume change. The current work reports the synthesis of carboxymethyl cellulose cmc and xylanbased homopolymerized as well as copolymerized hydrogels using an ethylene glycol diglycidyl ether crosslinker in alkaline medium.
Polyelectrolyte complexation versus ionotropic gelation for. Preparation, optimization and swelling study of carboxymethyl sago starch cmssacid hydrogel. Hydrogel composed of polyethylene glycol and carboxymethyl cellulose was prepared. Enhanced swelling and responsive properties of pineapple peel. Physically crosslinked polyvinyl alcoholhydroxyethyl. Synthesis and characterization of carboxymethyl starch for. Zno impregnated mcm41 nanocomposite hydrogel pdf free. Preparation and characterization of irradiated carboxymethyl. The resulting hydrogels were examined by running various experimental procedures such as ftir, xrd, and sem. In lab tests, the microparticles of the product, known as calciummodified carboxymethylstarch, swelled up to form a cohesive and adherent gel within 30 seconds after contact with blood. Radiation crosslinking of carboxymethyl starch request pdf. Sep 01, 2007 read influence of soluble polymer residues in crosslinked carboxymethyl starch on some physical properties of its hydrogels, starch staerke on deepdyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. Carboxymethyl cellulose hydrogels physicochemical characterization posted on.
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